Probing Factor-Dependent Long-Range Contacts using Regression with Higher-Order Interaction Terms

We propose a generalized linear regression with higher-order interaction terms to assess the influences of genomic features such as DNA-binding proteins and functional elements on long-range contacts from Hi-C experiments.


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1.3 by Raphael Mourad, a year ago

Browse source code at

Authors: Raphael Mourad

Documentation:   PDF Manual  

GPL-2 license

Imports IRanges, GenomeInfoDb, methods, GenomicRanges, Matrix, glmnet, rtracklayer, HiTC, MASS, S4Vectors

See at CRAN