A population genetic simulator, which is able to generate synthetic datasets for single-nucleotide polymorphisms (SNP) for multiple populations. The genetic distances among populations can be set according to the Fixation Index (Fst) as explained in Balding and Nichols (1995)
The R package
FILEST (Fine-Level Structure Simulator) is a population
genetic simulator. The simulator is able to generate synthetic datasets for
single-nucleotide polymorphisms (SNP) for multiple populations. The genetic
distances among populations can be set according to the Fixation Index (Fst).
This tool is able to simulate outlying individuals and missing SNPs can be
specified. For Genome-wide association study (GWAS), disease status can be set
in desired level according risk ratio.
The R package
Here is the list of functions in the R package
Install the released version of
FILEST from CRAN:
The source codes in this package include the Roxgen's syntax. If there is a
problem for generating the RD files (facing some errors) using RStudio (Build >
Document), try to use
roxygen2::roxygenise() instead of Build > Document
from the menu. Alternatively, install the package
devtools, then enable
RStudio to use the functions from
devtools (check Build > Configure Build
Tools... > use devtools package functions if available) or run
devtools::document() in the console.
When facing error for
testthat, try to update the package
testthat and add
Suggests: testthat in DESCRIPTION file.
Check the submission using
R CMD check --as-cran and a current version of
r-devel, as mandated by the CRAN Repository Policy. (You could do so using the
win-builder service at http://win-builder.r-project.org)
Check downstream dependencies with
Edit ~/.profile, ~/.bash_profile or ~/.bashrc, then add
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