Escalation with Overdose Control using 2 Drug Combinations

Implements escalation with overdose control (EWOC) trial designs using two drug combinations described by Tighiouart, Li and Rogatko (2017) . It calculates the recommended dose for next cohorts and perform simulations to obtain operating characteristics.


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install.packages("EWOC2")

1.0 by Quanlin Li, 2 years ago


Browse source code at https://github.com/cran/EWOC2


Authors: Quanlin Li and Mourad Tighiouart


Documentation:   PDF Manual  


GPL (>= 2) license


Imports MASS

Depends on rjags


See at CRAN