Escalation with Overdose Control using 2 Drug Combinations

Implements Escalation With Overdose Control trial designs using two drug combinations described by this paper (Tighiouart et al., 2016). It calculates the recommended dose for next cohorts and perform simulations to obtain operating characteristics.


Reference manual

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install.packages("EWOC.Comb")

1.0 by Yujie Cui, 2 years ago


Browse source code at https://github.com/cran/EWOC.Comb


Authors: Yujie Cui [aut, cre] , Quanlin Li [aut] , Mourad Tighiouart [aut]


Documentation:   PDF Manual  


GPL (>= 2) license


Imports MASS

Depends on rjags

System requirements: JAGS (>= 4.0.0). For installation instructions, see http://mcmc-jags.sourceforge.net/


See at CRAN