Sample Size and Power Calculations using the APPLE and SEPPLE Methods

Provides sample size and power calculations when the treatment time-lag effect is present and the lag duration is homogeneous across the individual subject. The methods used are described in Xu, Z., Zhen, B., Park, Y., & Zhu, B. (2017) .


Reference manual

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0.0.4 by Zhenzhen Xu, 4 years ago

Browse source code at

Authors: Zhenzhen Xu <[email protected]> , Boguang Zhen<[email protected]> , Yongsoek Park <[email protected]> and Bin Zhu <[email protected]>

Documentation:   PDF Manual  

GPL-2 license

Imports msm, survival

See at CRAN