Analysis of RNA Cytosine-5 Methylation

Bisulfite-treated RNA non-conversion in a set of samples is analysed as follows : each sample's non-conversion distribution is identified to a Poisson distribution. P-values adjusted for multiple testing are calculated in each sample. Combined non-conversion P-values and standard errors are calculated on the intersection of the set of samples. For further details, see C Legrand, F Tuorto, M Hartmann, R Liebers, D Jakob, M Helm and F Lyko (2017) .


Reference manual

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0.2.2 by Carine Legrand, a year ago

Browse source code at

Authors: C Legrand

Documentation:   PDF Manual  

GPL (>= 2) license

Imports MASS, graphics, stats, utils

Suggests IHW, testthat

See at CRAN