Bayesian Single-Arm Design with Survival Endpoints

The proposed event-driven approach for Bayesian two-stage single-arm phase II trial design is a novel clinical trial design and can be regarded as an extension of the Simon’s two-stage design with the time-to-event endpoint. This design is motivated by cancer clinical trials with immunotherapy and molecularly targeted therapy, in which time-to-event endpoint is often a desired endpoint.


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install.packages("BayesDesign")

0.1.1 by Chia-Wei Hsu, 9 days ago


Browse source code at https://github.com/cran/BayesDesign


Authors: Chia-Wei Hsu [aut, cre] , Haitao Pan [aut] , Jianrong Wu [aut]


Documentation:   PDF Manual  


GPL-2 license



See at CRAN