Case-Cotrol Analysis of Multi-Allelic Loci

Data sets and functions for chi-squared Hardy-Weinberg and case-control association tests of highly polymorphic genetic data [e.g., human leukocyte antigen (HLA) data]. Performs association tests at multiple levels of polymorphism (haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA, Mack SJ (2016) . Combines rare variants to a common class to account for sparse cells in tables as described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA (2012) .


Reference manual

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install.packages("BIGDAWG")

3.1.0 by Steve Mack, 5 months ago


https://github.com/IgDAWG/BIGDAWG


Report a bug at https://github.com/IgDAWG/BIGDAWG/issues


Browse source code at https://github.com/cran/BIGDAWG


Authors: Derek Pappas [aut] , Livia Tran [aut] , Steve Mack [aut, cre] , Jill Hollenbach [aut]


Documentation:   PDF Manual  


GPL (>= 3) license


Imports XML, haplo.stats, parallel

Suggests knitr, rmarkdown


See at CRAN