Integrative Inference of De Novo Cis-Regulatory Modules

Prior transcription factor binding knowledge and target gene expression data are integrated in a Bayesian framework for functional cis-regulatory module inference. Using Gibbs sampling, we iteratively estimate transcription factor associations for each gene, regulation strength for each binding event and the hidden activity for each transcription factor.


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install.packages("BICORN")

0.1.0 by Xi Chen, a year ago


Browse source code at https://github.com/cran/BICORN


Authors: Xi Chen [aut, cre] , Jianhua Xuan [aut]


Documentation:   PDF Manual  


GPL-2 license


Imports stats

Suggests knitr, rmarkdown


See at CRAN