Integrative Inference of De Novo Cis-Regulatory Modules

Prior transcription factor binding knowledge and target gene expression data are integrated in a Bayesian framework for functional cis-regulatory module inference. Using Gibbs sampling, we iteratively estimate transcription factor associations for each gene, regulation strength for each binding event and the hidden activity for each transcription factor.


Reference manual

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0.1.0 by Xi Chen, 3 years ago

Browse source code at

Authors: Xi Chen [aut, cre] , Jianhua Xuan [aut]

Documentation:   PDF Manual  

GPL-2 license

Imports stats

Suggests knitr, rmarkdown

See at CRAN